Huberman Lab discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For

My guest is Kyle Gillett MD a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health. We discuss how to optimize male hormones using a range of nutritional and behavioral tools exercise and supplementation (including discussions on tongkat ali fadogia agrestis creatine peptides and more). We explain how puberty and aging affect hormone levels how to use bloodwork to monitor hormone levels how hormone health impacts fertility libido hair loss and prostate health and describe behaviors that negatively impact testosterone levels. We also discuss how to approach prescription hormone therapies including which biomarkers to monitor when using these approaches and how to optimize synergistic hormones (e.g. growth hormone and thyroid hormone) to support complete hormone health safely and rationally. Dr. Gillett offers numerous actionable tools that can be tailored to specific goals and age ranges to attain and maintain optimal levels of male hormones for overall health well-being and longevity.  For the full show notes visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman ROKA: https://www.roka.com/huberman Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium Timestamps (00:00:00) Dr. Kyle Gillett & Male Hormone Optimization (00:03:40) Thesis ROKA Helix Sleep Momentous (00:07:43) Puberty: Height Resistance Training Childhood Obesity (00:15:14) “First” vs. “Second” Puberty (00:17:17) Hormone Optimization & Blood Work (00:22:14) Diet Exercise Sleep & Hormones (00:28:23) Hormones Stress Social Connection & Purpose (00:32:19) Hormones Supplementation & Medication (00:34:08) Determining Individual Hormone Levels ADAM Questionnaire (00:40:35) Libido Masturbation Pornography & the Dopamine “Wave Pool” (00:48:32) AG1 (Athletic Greens) (00:49:46) Sustainable Exercise Regimen for Hormone Health (00:58:12) Testosterone Replacement Therapy (TRT) (01:01:02) Supplementation: Creatine & Hair Loss Betaine L-Carnitine & Allicin (Garlic) (01:11:45) Vitamin D Boron; SHBG & Free Testosterone (01:15:34) InsideTracker (01:16:39) Tongkat Ali (Eurycoma longifolia; Longjack) & Steroid Pathways (01:22:09) Fadogia Agrestis & Testosterone  (01:26:32) Optimize Growth Hormone & IGF-1: Diet Fasting Supplements & Exercise  (01:31:52) Optimize Thyroid Hormone: Iodine & Goitrogens (01:33:56) Peptides: Growth Hormone Tesamorelin Ibutamoren & Gut Microbiome (01:42:06) Testosterone Therapy (01:47:03) Prescriptions & Hormones: Human Choriogonadotropin (HCG) Clomiphene (01:52:56) Testosterone Therapy + HCG Fertility & Temperature (01:55:30) Hormone Health Q&A: Marijuana Nicotine Cycling Pelvic Floor Alcohol Fat (02:06:08) Prostate Health & Tadalafil Prostate Specific Antigen (PSA) (02:09:56) Hair Loss & DHT; Turmeric & Curcuminoids (02:18:13) BPAs Phthalates & Hormone Health (02:21:55) Zero-Cost Support YouTube Feedback Spotify & Apple Reviews Sponsors Social Media Momentous Neural Network Newsletter Disclaimer Title Card Photo Credit: Mike Blabac

Dr. Kyle Gillett: Tools for Hormone Optimization in Males

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