Huberman Lab discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For

My guest this episode is Dr. Peter Attia M.D. who trained at Stanford University School of Medicine Johns Hopkins Hospital and the National Institutes of Health (NIH). Dr. Attia is host of The Drive podcast and is a world expert on behavioral approaches nutritional interventions supplementation and pharmacological techniques to improve lifespan healthspan and athletic performance. We discuss how best to evaluate your health status using routine blood work body scans and regular tests of physical strength and endurance. Dr. Attia explains what he uses with his patients to “back-cast” their health goals as a way to design their exercise and nutritional programs. We also discuss hormone modulation and replacement therapy for both men and women. We explain how cholesterol and related factors contribute to cardiovascular disease risk and how to monitor and mitigate that risk. Dr. Attia details various supplementation nutrition exercise and prescription approaches useful to people in every decade of life to improve vitality reduce their risk of disease and increase the number of years sustaining peak cognitive and physical health.  Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Maui Nui: https://mauinuivenison.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes visit hubermanlab.com Timestamps (00:00:00) Assessing Health Status & Improving Vitality  (00:02:51) Momentous Supplements  (00:03:46) AG1 (Athletic Greens) InsideTracker Thesis (00:07:29) Lifespan: Bloodwork & Biomarkers Testing The “4 Horseman of Disease”  (00:11:51) Healthspan: Functional Testing Cognitive & Emotional States  (00:13:59) Blood Testing: Best Frequency  (00:16:01) DEXA Scan: Lean Mass & Fat Bone Mineral Density & Osteoporosis  (00:22:33) Bone Mineral Density & Age-Related Decline Strength Training Corticosteroids  (00:29:24) Osteopenia & Osteoporosis Diagnosis Strength Training (00:31:03) AG1 (Athletic Greens) (00:32:16) Back-casting: Defining Your “Marginal Decade”  (00:38:31) All-Cause Mortality: Smoking Strength VO2 max  (00:44:43) Attia’s Rule of Supplementation “Centenarian Decathlete” Physical Goals (00:49:24) Importance of Exercise Brain Health MET hours  (00:55:23) Nicotine & Cognitive Focus (01:03:12) Menstruation PMS & Menopause  (01:10:10) Hormone Replacement Therapy Menopause & Breast Cancer Risk (01:22:06) Estrogen Progesterone & Testosterone Therapies in Women (01:26:35) Hormone Replacement Therapy in Men SHBG & Testosterone Insulin (01:37:23) Clomid Pituitary Testosterone & Cholesterol Anastrozole HCG (01:47:46) Fadogia Agrestis Supplements Rapamycin  (01:52:06) Testosterone Replacement Therapy & Fertility  (01:59:26) Total Testosterone vs. Free Testosterone (02:02:51) Cholesterol & Dietary Cholesterol Saturated Fat LDL & HDL Apolipoprotein B (02:17:42) Apolipoprotein B Diet Statins & Other Cholesterol Prescriptions  (02:25:15) Cardiovascular Disease Age & Disease Risk  (02:28:53) Peptides Stem Cells BPC157 PRP (Platelet-Rich Plasma) Injury Rehabilitation  (02:37:40) Metabolomics & Exercise  (02:40:44) GLP-1 & Weight Loss  (02:47:06) Zero-Cost Support YouTube Feedback Spotify & Apple Reviews Sponsors Momentous Supplements Instagram Twitter Neural Network Newsletter Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer

Dr. Peter Attia: Exercise Nutrition Hormones for Vitality & Longevity | Episode 85

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