Huberman Lab discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For

My guest this episode is Chris Palmer M.D. a board-certified psychiatrist and assistant professor of psychiatry at Harvard Medical School. He explains the important connection between nutrition metabolism and mental health and his pioneering work using the ketogenic diet to successfully treat patients with various mental illnesses including depression and schizophrenia. Dr. Palmer explains how the ketogenic diet is an evidenced-based treatment for epilepsy mimics the fasted state and can offset the cognitive decline in Alzheimer’s. He describes the key roles of mitochondria in mental health how certain conditions likely arise from mitochondrial dysfunction and how low-carbohydrate diets increase mitochondrial turnover to improve mental health. He also explains how low-carbohydrate diets positively impact the gut microbiome and weight loss important risk factors for mitochondrial health such as marijuana and alcohol and the best way to increase circulating ketones depending on individual needs. We also cover how a ketogenic diet impacts mood sleep and fertility. Dr. Palmer’s work stands as a revolutionary approach to mental health and disease that given the prevalence of mental health challenges should be of interest to people of all backgrounds and ages. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes visit hubermanlab.com Timestamps (00:00:00) Dr. Chris Palmer Mental Health & Metabolic Disorders (00:03:25) Thesis Eight Sleep ROKA (00:07:18) Nutrition & Mental Health (00:20:43) Low-Carb Diets & Anti-Depression Fasting Ketosis (00:27:52) Schizophrenia Depression & Ketogenic Diet (00:34:32) AG1 (Athletic Greens) (00:35:38) Psychiatric Mediations Diet Adherence (00:42:35) Highly Processed Foods Ketones & Mental Health Benefits (00:46:51) Ketogenic Diet & Epilepsy Treatment (00:56:10) Ketogenic Diet & Mitochondria Health (00:57:05) Nutrition & Benefits for Neurologic/Psychiatric Disorders (01:05:44) Mitochondrial Function & Mental Health (01:15:12) InsideTracker (01:16:23) Mitophagy Mitochondrial Dysfunction Aging & Diet (01:25:09) Neurons Mitochondria & Blood Glucose (01:31:54) Obesity Ketogenic Diet & Mitochondria (01:40:00) Mitochondrial Function: Inheritance Risk Factors Marijuana  (01:46:34) Alcohol & Ketogenic Diet (01:55:21) Brain Imaging Alzheimer’s Disease & Ketones (02:01:05) Exogenous (Liquid) Ketones vs. Ketogenic Diet (02:06:27) Neuronal Damage Ketones & Glucose  (02:10:16) Alzheimer’s Disease Age-Related Cognitive Decline & Ketogenic Diet (02:23:45) Ketogenic Diet & Weight Loss (02:35:47) Ketogenic Diet & Fasting Hypomania Sleep (02:46:37) Low Carbohydrate Diets Menstrual Cycles Fertility (02:52:23) Obesity Epidemic Semaglutide & GLP-1 Medications  (03:01:01) Zero-Cost Support YouTube Feedback Spotify & Apple Reviews Sponsors Momentous Supplements Neural Network Newsletter Social Media Disclaimer Title Card Photo Credit: Mike Blabac

Dr. Chris Palmer: Diet & Nutrition for Mental Health | Episode 99

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